What is cml concept?

CML stands for Chronic Myeloid Leukemia, which is a type of blood cancer that affects the bone marrow and blood cells. It is also known as Chronic Myelogenous Leukemia or Chronic Myelocytic Leukemia. CML is caused by a genetic mutation that results in an abnormality called the Philadelphia chromosome, which causes the bone marrow to produce too many white blood cells.

The symptoms of CML include fatigue, weight loss, fever, night sweats, pain or discomfort in the abdomen, and enlarged spleen. The diagnosis is usually made through blood tests and bone marrow biopsy.

Treatment for CML often includes medication, such as tyrosine kinase inhibitors, which help to control the production of white blood cells. In some cases, a bone marrow transplant may be necessary. With proper treatment, many people with CML are able to live a normal life.

CML is considered a chronic cancer, meaning that it can be managed over a long period of time, unlike acute leukemia, which requires more aggressive treatment and has a worse prognosis. CML is relatively rare, accounting for about 15% of all cases of leukemia.